As far as control, yes I would say so. You just can't remove the electronics out of it. There isn't any way to control the trans effectively without the electronics and some sort of computer.
Earlier 4spd electronic trans like the 4l60, 4l80, and AW4 are really just simple hydraulic auto transmissions that used solenoids to do what the governor and kickdown cable systems used to do. Its not hard to pull the solenoids out and control it manually. These new transmissions like the 6l80, 8l90, ZF8HP are a whole different breed of trans. There are some interesting possibilities with transmissions like these, but you have to be comfortable with computer systems.